月度归档： 2025 年 4 月

30 years after foreign pharmaceutical companies entered China, Lilly, Pfizer and Merck’s new ways of playing.

This article comes from WeChat WeChat official account:Deep blue view (id: mic-sh 366), Author: Gao Yi, editor: Wang Chen, head picture from: vision china.

In May, 2023, with the latest data of the most Alzheimer’s disease drug from Lilly, this century-old pharmaceutical company continued to sound the upward horn, and its market value climbed to the $400 billion mark, becoming the most valuable pure drug enterprise in history.

When the stories in the field of cancer were exhausted, the investors on Wall Street found the track of "losing weight" and continued to write the myth that the pharmaceutical industry will always go up, which also contributed to the market value growth of Novo Nordisk and Lilly this year. Years of hard work in the CNS field has added a icing on the cake to Lilly.

However, Lilly global is flourishing, and the voice of Lilly China seems to be getting smaller and smaller this year.

Lilly’s last big event in China was the 2022 new medical insurance catalogue at the beginning of this year. Four new products/indications successfully entered medical insurance, including two cooperative products from Cinda. In the past year, the only pipeline renewal that can be seen in China, one is RET inhibitor and the other is a hair loss product, which obviously goes against the thickness of Lilly global’s powerful product pipeline.

Photo: Lilly’s Q1 product performance in 2023.

Source: official website, Jibao finishing

From the time point of view, Lilly is one of the first batch of big manufacturers to bet on China. As early as 2012, Lilly moved its R&D center to China, trying to speed up the listing of global products in China. However, the R&D center in China District opened early and closed early. Perhaps it is the long-term single-digit income ratio in China District, which makes this MNC factory unwilling to invest more energy in cultivation;The rise of local enterprises in these years has also had some run-on effects on foreign enterprises to some extent. In 2022, Lilly’s China business contracted to 1.453 billion US dollars, down by 10 percentage points.(Source: Huachuang Securities).

More than courtesy, under the double pressure of competition between VBP and local enterprises in the past two years, the domestic business of multinational giants has shrunk. One is that the speed of introducing products from foreign companies is slower than in previous years, and the other is that the demand for talents is becoming more and more Buddhist.

A headhunter said that since the second half of last year, the recruitment needs of foreign pharmaceutical companies in all functions, whether business or clinical, have declined; Some non-business core positions that were quite popular a few years ago(such as "digital innovation", etc.)In the past two years, it has almost disappeared completely.

The basic executive positions such as medical representatives were originally the most mobile, but the post pattern has not changed much in the past two years. A person who pays attention to this kind of market mentioned that this is related to the slow iteration of new products in the past two years. Even if new products are listed, they are basically handed over to the original team to do it together. For example, BMS set up a separate team for PD-1 in 2018, which has not been seen in the last two years.

However, although Lilly’s pharmaceutical business in China is operated by Buddhism, it does not prevent Lilly from embracing the rapid growth of this emerging domestic market in other ways. For example, Lilly cooperates with Hutchison and Cinda to help them bring their products to the market, even to Europe and America, and use the resources of their own big factories to earn a share of the money; Another example is LAV, which is synonymous with the success of domestic biomedical first-level investment.

Neither the introduction/authorized cooperation nor the next incubation is exclusive to Lilly. Other multinational pharmaceutical companies have been running in China for nearly 30 years, and now they are slowly adapting to the ever-changing new market with some comfortable postures.

First, "retreat to the high-end route"

In January, 2023, the annual meeting of Huizhi, which was formed by the merger of Pfizer’s mature business units Puqiang and Mylan, was held in Macau, with an exceptionally grand scale.

Behind the luxury annual meeting is its solid growth. According to a participant, Huizhi’s in-hospital sales data this year is obviously better than expected, and the business authorities dare not talk about the specific figures too high-profile, but only give a growth curve that looks obviously upward. Last year’s Huizhi, the bonuses of the sales teams were also exceptionally good.

The number of hospital growth data of Huizhi China is unknown, but from the financial report of Huizhi last year, Greater China was in Q4 last year.(after the epidemic)Year-on-year growth reached 10%. Last year, China earned 2.201 billion US dollars, making it the only market with positive year-on-year growth in net profit.

The main driver of the growth of Huizhi China is Lipitor.(atorvastatin)Luo huoxi(amlodipine)And Xanax(Alprazolam)Among them, the first two were included in the national procurement catalogue long ago. This makes the whole market rethink a question:Is volume a good business after all?

Although the head foreign companies represented by Pfizer and AstraZeneca have launched a series of "grassroots" movements in the past few years, in 2021, Pfizer’s grassroots team reached 600 people, and AstraZeneca’s county team reached a maximum of 4,500 people.

At first, everyone’s idea was to be in a vast market with a super large base. Every 1 percentage point increase in penetration rate is a big increase in the overall scale. However, the following nationwide procurement with quantity not only greatly reduced the profit margin of drugs, but also introduced a large number of "barefoot" players who had never paved the way for the market, which made the "grass-roots strategy" of these large foreign companies a decoration.

Considering the welfare and per capita output, the sales efficiency of foreign pharmaceutical companies is inherently inferior to that of local players, so they can only "retreat" to the high-end market.

Of course, choosing a "high-end market" also requires selective capital. "High-end" doesn’t really mean that products are much higher than competitors in quality and clinical data, but more is a process of brand and doctor-patient psychological cognition, which is inseparable from the long-term market education made by these big manufacturers and the dozens of academic forums that have been smashed in the past decade.

Therefore, sales is not a simple "department meeting" and a dinner party. Whether it is a foreign pharmaceutical company or a local rising star, if you really value your products, the work of the marketing department is indispensable. It should be pointed out that this budget often needs to be integrated into the pricing of a drug.

Both centralized purchasing and medical insurance negotiation can solve the problem of "accessibility" to a certain extent, but the effective use of drugs also needs the promotion of pharmaceutical companies themselves.

Back to Pfizer’s business in China, as long as this "high-end" strategy can still operate normally at present, new products from global will be continuously injected and then profits will be contributed to the world.

This kind of "China agent of multinational pharmaceutical companies" business is also the most classic and good game for foreign pharmaceutical companies. Pfizer is doing it, and Takeda, Novartis, GSK and so on are basically following this strategy at present.

When the global products of these multinational pharmaceutical companies are not strong enough, these companies will also make some deeper attempts in China.

Second, BD cooperates to make a fire by the stove.

Among them, the most representative belongs to Merck.

Although the ceiling of tumor immunotherapy and drug K have now become the proper "drug king", Merck has actually had nothing to do with the treatment field of tumor for a long time.

Merck secured the TOP5 position in the world with simvastatin and losartan. Since then, it has been supported by two major categories: anti-infection and vaccine, and has made heavy income in several sub-sectors such as AIDS, hepatitis C and HPV. Therefore, even in the early 21st century, Roche’s three monoclonal antibodies have already begun to take shape, but the proud Merck seems to have no need to know what antibody drugs are, so he met Schering-Plough.(K medicine source prescription)Before, there were almost no macromolecular products in Merck’s laboratory.

In the second decade, biopharmaceuticals slowly moved to the center of the stage. Half of the TOP10 best-selling products in the world were protein drugs, and Merck himself tasted the sweetness of K drugs. However, the cultivation cycle of biomedical technology needs to be calculated in ten years. It is not easy for Merck, which lacks macromolecular genes, to come up with a mature antibody drug platform to adapt to the pipeline development of such a billion-dollar giant in a short time.

So,When ADC took over the immune products and went to the foreground, Merck, who couldn’t wait, had to put down his body and seek external cooperation.

Therefore, Merck found Seagen, the "originator of ADC", because of his great family business. However, Seagen, whose price has been difficult to negotiate, ended up with Pfizer, which paid an extra $12 billion directly to intercept Hu Merck.

Merck, on the other hand, had to focus on Collen, an old friend of China, and directly won nine ADC molecules in one breath, which was less than a quarter of Seagen’s acquisition even if all the total package prices were included. Merck’s deal could not be said to be uneconomical.

In May this year, Ms. Ji Juan, the head of Merck’s business development and authorization in Greater China, mentioned at the third Sequoia Global Medical and Health Industry Summit: "Merck’s product introduction is distributed in various treatment fields, clinical stages and different mechanisms." Merck will not only focus on one or two big therapeutic fields now, as long as things are good, it can be digested. To some extent, it also reflects the comprehensiveness of large factories.

Merck’s eclectic products contributed half of the company’s revenue last year. If the ADC field continues to deepen and become more and more accepted by the global market, a considerable part of Merck’s tens of billions of dollars in revenue in the future may come from laboratories in China.

With the domestic R&D-clinical capability reaching a higher level, it is not uncommon for China to feed back the world.License out has also become a commonplace topic.But an interesting point is that the number of domestic and foreign authorizations and the total amount of cooperation are increasing, but the down payment is decreasing.

On the one hand, "returns" have become more frequent in the past two years, such as the ADC of Genting Xinyao, the PD-1 of Cinda, and the BTK of Nuocheng Jianhua, which has reduced the certainty of this authorized cooperation;

On the other hand, whether local enterprises or partners, everyone is more willing to seek innovation in the model, and both sides make a concession and take what they need to tell the story more satisfactorily. For example, Cinda and Sanofi, and for example, Merck and Columbine Botai, both of which are mixed with equity transactions.

However, in a mature market, the BD transaction of License in/out itself is a very common thing. The details such as transaction amount, down payment, object and method only reflect the strategic choice of participants at this time node. When the valuation is high, the efficiency of self-research is higher than that of external mergers and acquisitions, and when the industry is deserted, large companies with spare money are more suitable for expansion.(rather than self-research).

The diversification and normalization of BD cooperation shows that the biomedical market in China is slowly maturing.

Third, hatch in person

After the dissolution of AstraZeneca China R&D Center, it became Di Zhe. After running for less than three years, it landed in science and technology innovation board and rose from the bottom of last year, and its share price tripled at the highest. AstraZeneca, as a major shareholder accounting for 26% of the shares, in addition to the premium on financial investment, it can carry out in-depth cooperation on the product pipeline through Dizhe in the future.

More importantly, AstraZeneca can use the business card Dizhe to do some deeper cooperation in finance and project mergers and acquisitions in the future. A typical example is AstraZeneca Zhongjin Medical Industry Fund, which was established with CICC the year before last. It is very comfortable in fundraising and investment, and currently holds 13 medical and medical projects. AstraZeneca’s business in China is increasingly diversified.

In addition to AstraZeneca, Deqi Medicine, which was established in 2016 with the support of Xinji Medicine, a leading global biopharmaceutical company, also has a little "incubation nature".

The founder of Deqi Medicine comes from the R&D executives of Xinji. Half of the main projects come from Xinji, and some of the money from Angel Wheel just landed is given by Xinji. However, considering that Xinji’s share in Deqi was less than 6% at the time of IPO, it was not controlled, but it was an enterprise hatched by Xinji after all.

What can be controlled is called "incubation", and what can’t be controlled can only be called "deep cooperation"In addition to Deqi, another big hand of Xinji is Baekje.

In 2017, Xinji awarded a cooperation with a total amount of US$ 1.393 billion, which not only helped Baekje just listed on the US stock market, but also boosted its prosperity. At the same time, it used its own mature products and the commercialization team of Xinji Company acquired by Baekje in China to promote Baekje to establish a commercialization system.After this cooperation, Baekje was arrogant all the way, and the market value of US stocks almost caught up with Japan’s MNC giant Takeda. However, Xinji itself sold herself to BMS in 2019, and this cooperation was suspended. The "breakup" between Xinji and Baekje may have been doomed.

Amgen replaced Xinji and continued to cooperate with Baekje in depth, which is also "giving money and products". Perhaps it is more optimistic about the potential of this company. Unlike Xinji, Amgen directly turned itself into a major shareholder of Baekje.

It is worth mentioning that nowadays, the cooperation between multinational pharmaceutical companies and local companies is more and more diversified, not limited to one or two ways.

For example, Baekje and Amgen are deeply bound, and Baekje also supports the construction of its tumor pipeline to Novartis License out products, while the latter, while the pipeline is supplemented, can also empower Baekje to commercialize in the world;

Furthermore, AstraZeneca’s cooperation with the local area can be described as "dazzling": green leaf exchange products, binding with Internet channel geeks, introducing the ADC of No.1 and No.3, and introducing the ADC of Connoa/Lepu Bio at the same time … As for other sales and market cooperation, there are countless more.

The reason why foreign companies are more and more willing to play is that the rules of the game are more and more fair.

In the past two decades, a few domestic enterprises have the ability to develop compound technology to meet the differentiated needs of the low-level market that foreign pharmaceutical companies cannot cover. Most so-called pharmaceutical companies only earn coins in the circulation field.

With the improvement of the independent ability of the pharmaceutical industry, the wave of innovation is superimposed. From following imitation to innovation self-sufficiency to "in China for global", the productivity of foreign companies’ products is no longer suppressed, and the policy protection of local pharmaceutical companies is becoming more and more negligible. Everyone is playing together at the same level and conditions.

Behind this is the growing maturity of the entire pharmaceutical industry in China.

Maturity also means that local pharmaceutical companies need to abandon the luck of "home advantage" and come up with 100% strength to compete with these large foreign companies with a history of 100 years.

This article comes from WeChat WeChat official account:Deep blue view (id: mic-sh 366), Author: Gao Yi, Editor: Wang Chen

Sun Jun, the winner of the special government allowance of the State Council and the chief forecaster of the Central Meteorological Observatory： I watched Yun Qi’s poor efforts.

"As a forecaster, I hope I can understand the secret and draw the forecast closer to the reality." Sun Jun, the chief forecaster of the Central Meteorological Observatory, has been a forecaster all his life, from a handsome young man to an old comrade with white temples. From using pencils to using artificial intelligence, he has been understanding the secret all his life.

On December 1, 2023, Sun Jun judged the closing ceremony weather of the Pacific Games at the Solomon Islands Meteorological Bureau. Figure/Jing Hao

Exploration-the scientific mystery in the clouds

"Experienced ups and downs, find the law in the changing situation. When the forecast is successful, it is not too joyful; When the forecast fails, don’t be too upset, and constantly explore and improve the forecast. " Sun Jun said.

After doing one thing all his life, Sun Jun thought about it for a while and simply gave the word "worth it".

"The flood in Jilin in 2010, the torrential rain in Beijing on July 21, 2012, the torrential rain in Henan in 2021, and the extreme rainstorm in Beijing, Tianjin and Hebei in 2023 …" Talking about the past, many weather processes are clearly visible in Sun Jun’s mind.

He often gets to the bottom of the weather. And this curiosity began from childhood. When I was a child, Sun Jun saw a neat cloud boundary in the dark sky: the sky was overcast on one side and Wan Li was clear on the other. He is full of curiosity: what is this?

This "why" continues to work. "Dealing with the weather is also my initial intention to explore scientific issues." Sun Jun said.

Find problems in forecasting, solve problems in scientific research, and apply research results to business, thus further improving forecasting accuracy. Sun Jun observed, discovered, analyzed and verified over and over again, and carried out a cycle from forecasting to scientific research to forecasting.

In July, 2021, due to the rich water vapor brought by the typhoon landing, a torrential rain occurred in Henan. Sun Jun and his team once included the rainstorm affected by typhoon landing in the research scope.

……

Time and time again, the scientific research topics were condensed-warm rainstorm, typhoon rainstorm and extreme rainstorm. Sun Jun and his team found clues of scientific problems from the forecast process.

After continuous research, scientific research has also made a series of progress. In the diagnosis of extreme rainstorm, the water vapor condition, dynamic condition and thermal condition are diagnosed and analyzed, and the abnormal meteorological factors causing extreme rainstorm are screened.

In 2023, the forecast accuracy reached a new high, and the score of 24-hour rainstorm increased to 98% compared with the mainstream model, reaching the highest level in history.

It is the confidence brought by continuous exploration that allows him to confidently give the conclusion that "it won’t rain" in the face of complex weather situation in the forecast of Hangzhou Asian Games.

Responsibility-Forecast and Early Warning in Storm

"I always say that human life is related to the sky, and the sky here refers to the weather." Weather is closely related to the safety of life and property. Therefore, he has a strong sense of mission and responsibility. "If the forecast is accurate, we can better prevent and respond, and we can keep safe." Sun Jun said.

In order to catch up with time, he is always the first to arrive at work when he is on duty. "Sun Jun is a respected old forecaster and very dedicated." Zhang Tao, chief forecaster of the Central Meteorological Observatory, said.

Sun Jun recalled the flood in Jilin in July 2010, and was faced with the judgment of whether the reservoir needed flood diversion and whether the dam needed blasting. "This is a major test." After careful analysis, Sun Jun and his colleagues accurately judged the precipitation level.

In July 2023, a rainstorm occurred in Beijing, Tianjin and Hebei. Sun Jun "recalled" the weather process in his memory, thinking that it was similar to the "July 8" rainstorm in Henan, and it was extremely extreme, so he raised the forecast precipitation. Later, it was proved that this adjustment was correct.

With global warming and frequent extreme weather, many data exceed the extreme value, which breaks through the forecaster’s original cognition and increases the difficulty of forecasting.

Adhering to a scientific and rigorous attitude, Sun Jun is not afraid to challenge the numerical model prediction. "It’s always calm when things change." Yang Shunan, chief forecaster of the Central Meteorological Observatory, commented on Sun Jun this way.

Colleagues gave Sun Jun a nickname, "Sun 500", which came from a bold and cautious forecast. From June 17th to 21st, 2010, a rainfall process occurred in the northeast of Jiangxi. Sun Jun gave the forecast conclusion of the maximum precipitation of 500mm. This is a bold forecast, which is much higher than the conclusion of the numerical model. After analysis and verification, his prediction conclusion is accurate. Sun Jun teased that if the forecast was not accurate, it would be called "Sun 250".

"Because there is always uncertainty in forecasting, there is always pressure." Under the calm appearance, Sun Jun also has his own pressure. On many nights when rain is predicted, he will wake up and look at the sky. On the day of duty, he will be slightly gaunt when he is full of energy.

Pursuit-the precision of time and space

In the late 1980s, Sun Jun joined the Central Meteorological Observatory. On the topographic map with provincial boundaries, Sun Jun draws the weather map with a 2B pencil and red and blue pencils. "At that time, there was a lack of forecast data and there was no precipitation data to refer to. A clever woman can’t cook without rice. " Sun Jun said.

With the development of science and technology, with the blessing of satellites, radars and automatic weather stations, the observation data and information are more abundant. "The temporal and spatial resolution of the forecast is more refined." Sun Jun said.

The technology is changing, and Sun Jun’s love for forecast maps remains unchanged. "Drawing weather maps is a pleasure." In his view, synopsis is a subject dealing with data. In order to better compare historical cases in forecasting, Sun Jun keeps the weather maps and key physical quantities of many weather processes in mind.

"To be an excellent forecaster, you need not only excellent professional knowledge, but also knowledge of astronomy, geography, politics and economics." The understanding of social economy also enables Sun Jun to better serve the weather forecast in production and life. Before Spring Festival travel rush this year, Sun Jun predicted the cold wave weather in advance. Considering the impact of road icing on Hubei, Henan, Anhui and other places, he recorded an interpretation video.

In 2025, Sun Jun reached the age of retirement. At present, in addition to doing a good job in weather forecasting, he has also shifted his focus to personnel training: leading the team to tackle key scientific research problems and teaching … Liu Yi, the global meteorological office of the Central Meteorological Observatory, said, "There is laughter everywhere."

At the same time, Sun Jun also participated in global monitoring, forecasting, service and other work, making forecasts in a larger world and passing on his experience to more people.

"Now, the pursuit of weather forecasting is fixed-point, fixed-time and quantitative. As long as the accuracy rate has not reached 100%, we must continue to explore and be a dream catcher forever." Sun Jun said.

(author:Xu Nenyu Editor: Zhang Lin)

Sichuan： Activating the ＂Waste-free Cell＂ in the City with Tax and Fee Concessions

This year’s government work report proposes to strengthen the construction of ecological civilization and promote green and low-carbon development. Implementing this requirement and speeding up the construction of a "waste-free city" is an important starting point.

"Waste-free city" is an advanced urban management concept and a development model. By promoting the formation of green development mode and lifestyle, we will continue to promote the reduction of solid waste sources and resource utilization, minimize landfill disposal, and minimize the environmental impact of solid waste. In April, 2022, the Ministry of Ecology and Environment released the list of "Waste-free Cities" during the Tenth Five-Year Plan period, including Chengdu, Yibin, Leshan, Zigong, Luzhou, Deyang, Mianyang and Meishan in Sichuan.

In order to help build a "waste-free city", Sichuan tax authorities continued to implement the new development concept, focused on the actual needs of enterprises, and compiled the Guidelines on Tax Preferential Policies to Support Green Development. They made precise efforts from four aspects: supporting environmental protection, promoting energy conservation and environmental protection, encouraging comprehensive utilization of resources, and promoting the development of low-carbon industries, refined 66 measures to implement tax preferential policies, and comprehensively guided enterprises to go green.

From "Overdischarge" to "Pollution Reduction" —— Tax incentives inject impetus into green transformation

Source pollution reduction is the core part of the construction of "waste-free city" The traditional industries that reduce pollution at the source and develop extensively must do a good job of green transformation and upgrading.

As the "western porcelain capital", Jiajiang County of Leshan City has a long history of pottery making, and pottery making is also one of the local pillar industries. In the era when coal is the main energy source for pottery making, Jiajiang County has been suffering from high pollution and high energy consumption in pottery making, and the huge sewage cost has also seriously hindered the survival and development of enterprises.

"The greater the energy consumption, the higher the tax cost, the higher the product cost and the lower the competitiveness." Luo Qizhou, the legal representative of Jiajiang Huaxing Ceramics Co., Ltd., said frankly. In order to enhance the competitiveness of products, enterprises continue to improve traditional technology and increase investment in environmental protection, and in 2023 alone, they will enjoy more than 300,000 yuan of environmental protection tax relief. "With the 300,000 yuan saved by tax reduction and exemption, we have introduced two new production lines using natural gas, which are cleaner than the previous coal production and the energy consumption has dropped significantly." Luo Qizhou said.

From "super discharge" to "pollution reduction", the story of green transformation of Huaxing ceramics is only a microcosm of the structural transformation and green breakthrough of traditional industries. Nowadays, in Sichuan, a large number of traditional industrial enterprises, represented by ceramic production enterprises in Jiajiang County, are constantly activating "waste-free cells" through a series of advanced technologies of energy saving and carbon reduction, such as changing coal into gas and upgrading production lines, and upgrading the former high-pollution and high-energy-consumption industries into dynamic industries with "green" content and "new" content.

In order to enable enterprises to gain more external force in solving problems, Sichuan tax authorities have also deepened the pattern of multi-governance and efficient coordination, strengthened cooperation with ecological environment, natural resources and other departments, jointly established an information sharing platform for environmental protection tax, focused on high-pollution and high-energy-consuming enterprises, established a dynamic database, strengthened the comparative analysis of basic data, consolidated the foundation of taxation according to law, and built a "tax collection and management, enterprise declaration, environmental monitoring, information sharing, and"

Drawing "Green Meaning" with "Zero Carbon" —— Intimate Service Empowers Enterprises to Seize the New Track

The construction of "waste-free city" is connected with pollution reduction at one end and carbon reduction at the other. Recently, the State Council promulgated the Interim Regulations on the Management of Carbon Emissions Trading, which clarified the carbon emissions trading system in the form of administrative regulations for the first time. The data shows that as of the end of last year, the cumulative turnover of the national carbon emission trading market reached 440 million tons, with a turnover of about 24.9 billion yuan. Aiming at "zero-carbon competitiveness", green and low-carbon has become the consensus of high-quality development.

Sichuan Times New Energy Technology Co., Ltd., located in the eastern industrial park of Yibin Sanjiang New District, is the world’s first "zero carbon factory" for batteries. From the beginning of preparation, enterprises have planned a "zero carbon" path, and through continuous transformation and innovation in manufacturing and energy utilization, they are committed to making more products with low carbon competitiveness with less raw materials while reducing carbon emissions.

"On the road of green development of enterprises, the tax authorities are accompanied all the way." The relevant person in charge of Sichuan Times New Energy Technology Co., Ltd. said. According to reports, Yibin tax department has set up a service team of "direct connection between tax enterprises" to form an integrated "identification-analysis-treatment-result" process of "policy finding", equipped with "exclusive grid staff" to push the tax policy to legal representatives, financial personnel and tax collectors in a time-sharing and hierarchical manner to ensure accurate direct access to enterprises. In 2023, the company enjoyed a total of about 2.5 billion yuan in tax benefits such as export tax rebate, consumption tax and urban maintenance and construction tax.

Under the guidance of Sichuan Times New Energy Technology Co., Ltd., many enterprises in Yibin power battery industry chain have also achieved the advanced stage of "zero carbon". Yibin Libao New Materials Co., Ltd., which produces raw materials in the upstream of the industrial chain, Times Geely Power Battery Co., Ltd., which produces batteries in the midstream, and Sichuan CRRC Rail Transit Co., Ltd., which produces complete vehicles in the downstream, have successively obtained the certification of "zero carbon factory".

"A few days ago, the ecological and environmental departments of Sichuan and Chongqing issued the first inter-provincial" Regulations on the Construction and Management of Waste-free Urban Cells (Trial) "to further standardize the construction of waste-free urban cells in the economic circle of Chengdu and Chongqing." The relevant person in charge of Sichuan Provincial Taxation Bureau in State Taxation Administration of The People’s Republic of China said that Sichuan taxation department will constantly sum up experience and innovate service measures, continue to give full play to the role of taxation functions, strengthen the linkage between Sichuan and Chongqing taxation and cross-departmental coordination, so as to release greater effectiveness of various tax incentives and promote enterprises to make steady progress in the fast lane of green development and transformation.

Questioning ＂artist’s sudden death＂： AED is far from the requirement of ＂golden 4 minutes＂

　　one

　　Gap of equipment

　　"Shenzhen and Shanghai are the cities with the best configuration of AED in China, especially Shenzhen, which still has a lot of AED equipment, but when we calculated last year, its level was one within an average of 1.5 kilometers, which could not reach ‘ 4 minutes ’ This requirement. "

　　2

　　Cost gap

　　"At present, there is no unified management organization for AED equipment, and buyers or donors are also different." "A machine of around 30,000 will cost a lot if you want to popularize it. Where does this fee come from? Which institution can pay the bill? "

　　three

　　A gap in consciousness

　　"We not only lack first-aid knowledge and skills, but also first-aid equipment, such as first-aid kits and AEDs, and what we lack is first-aid awareness." "In the past, everyone thought that pre-hospital first aid had to wait for 120. I was unprofessional and I could do nothing."

　　From Xu Yong, editor of Xinhua News Agency, to Godfrey Tsao, an artist, their sudden death is regrettable, and the "life-saving artifact" AED (automated external defibrillator) is once again hotly debated. AED, known as the "life-saving artifact" in the front line of life and death, is it configured in real life, is it used correctly, and does it really enter the lives of ordinary citizens?

　

　　Recently, Chengdu Business Daily-Red Star journalists conducted many investigations and found that although the first-aid knowledge such as pre-hospital first aid and cardiopulmonary resuscitation (CPR) has entered the public’s field of vision in recent years, the popularization of AED in China is still unsatisfactory. The popularity of AED in public places is far from the requirement of "golden four minutes" treatment.

　　Relevant personnel of the Relief and Rescue Department of the Red Cross Society of China said in an interview with Chengdu Business Daily-Red Star News reporter that AED equipment can really improve the success rate of treatment, but it is more important to popularize first aid knowledge. Many people in the industry have revealed that the lack of AED is only a "microcosm", reflecting the lack of public awareness of first aid.

　　If you want to find out where the nearest AED is, the WeChat applet "Help Map" can do it. First Response, an emergency training institution, is the developer of the program. Lisa, its co-founder, told Chengdu Business Daily-Red Star journalist that the "life-saving map" can provide the location of the nearest AED equipment according to the user’s location, and jump to an external map program for navigation.

　　By looking at the "life-saving map", the reporter noticed that the distribution of AED equipment in Beijing included in the map was uneven: in Chaoyang District, for example, in the core areas of Sanlitun and Guomao, the layout of AED equipment was relatively dense, but in the areas near Jiulong Mountain and Baiziwan in the southeast, the number of AED equipment was very small. The reporter searched for a nearby AED device in Heshenghui Shopping Mall through the "life-saving map", which is located on the fifth floor of the office building across the street. The equipment attribute is donated by the enterprise. The reporter found that the company could not take out the equipment for use after work. The contact person of the AED equipment told the reporter that the equipment is managed by his own company and can also be lent to the public for use, but it is almost never lent. The contact explained that, considering the risk of loss and other reasons, the equipment has always been stored in the store, so employees can’t be taken out after work.

　　Where have all the AEDs in Beijing gone? It is understood that at present, AEDs in Beijing are mostly located in airports. According to the Beijing Daily, up to now, there are 69 AED devices and 8 spare devices in the three terminals of the Capital Airport, which are distributed in crowded areas such as check-in area, waiting area, entrance passage and baggage hall. In Beijing Daxing International Airport, 40 AED devices have been installed.

　　AED faces three dilemmas.

　　"Every time a student asks me where I can see AED besides the airport, I feel very embarrassed. Indeed, we have not popularized it." Shi Hong, the captain of the first-aid team of Beijing Emergency Volunteers Corps and the director of the American Heart Association (AHA), has been doing public promotion teaching of AED for 10 years, but he found that every hot search on AED is still based on the occurrence of sudden death. As soon as the heat of the incident passed, everyone put the matter aside.

　　Shenzhen with the best configuration

　　Also can not meet the "4 minutes" requirement.

　　Shi Hong traveled all the year round for emergency rescue training. He found that the popularity of rescue culture in Beijing was higher than that in other cities, but the AED setting was far from enough. He was deeply impressed by Shanghai and Shenzhen, where the number of AEDs was relatively large, but only for the national average, it could not meet the four-minute rescue demand of gold.

　　Lisa is deeply touched. She said that under ideal circumstances, shopping malls, subway stations, airports, high-speed railway station and other public places should be equipped with AED equipment, but at present, the actual configuration of AED equipment in China is far from the requirements. "At present, Shenzhen and Shanghai are the cities with the best AED configuration in China, especially Shenzhen, and its number of AED equipment is still large, but when we calculated last year, its level was one within an average of 1.5 kilometers, which is not up to ‘ 4 minutes ’ This requirement. "

　　"Golden 4 minutes" is the best rescue time recognized by the industry. "Ideally, an AED device should be deployed within 4 minutes’ walk from the accident site." Lisa said that the sooner the patient performs cardiopulmonary resuscitation (CPR) and cooperates with AED equipment in the "golden 4 minutes" after falling to the ground, the better the survival rate of sudden death.

　　30 thousand yuan a set

　　Who will pay the bill is a question.

　　But the present situation is not satisfactory. Why are AEDs so "scarce"? Who will pay the bill is also a problem. "At present, there is no unified management organization for AED equipment, and buyers or donors are also different." Lisa said that the AED equipment currently included in the "life-saving map" and seen in public places may come from the unified procurement of the local health and health commission, the civil affairs bureau, the emergency management bureau or the Red Cross, and may also come from donations from charitable organizations or enterprises.

　　"There is no unified wind direction, and it is all based on their own push." This is Shi Hong’s feeling. Despite everyone’s efforts, the strength is still "very loose". This also leads to a real problem, "a machine of about 30 thousand will cost a lot if it wants to be popularized." Where does this fee come from? Which institution can pay the bill? " Shi Hong feels that there is demand in society now, but there are too few equipments.

　　With the equipment

　　Dare to use it, will it be used?

　　Jia Dacheng, a retired doctor from Beijing Emergency Center, who is known as "the first person in China’s first aid education", told Chengdu Business Daily-Red Star News reporter that nine times out of ten emergency cases he experienced were rescued by AED, and only one or two were saved by hand-held cardiopulmonary resuscitation. Another data shows that the success rate of cardiopulmonary resuscitation with AED is 60%~70% higher than that without AED.

　　Even with the equipment, where it is, will the public dare to use it or not?

　　Although many experts told Chengdu Business Daily-Red Star News reporter that AED is simple to operate, just turn it on and follow the voice prompts. But at the same time, they also told reporters that people who have not received training often dare not use it and are afraid of taking responsibility; Those who master the relevant first aid knowledge are still considered as "minorities" in China.

　　Lisa told reporters that they had done relevant investigations. At present, people’s understanding and understanding of CPR skills in China is only at the level of "barely passing". "Although everyone has learned about CPR through various channels, there should not be many people who can do it right in case of unexpected events without practical operation."

　　Lisa stressed that compared with the United States and Japan, our mastery rate of cardiopulmonary resuscitation skills is only one thousandth of theirs, including the use of AED equipment.

　　Zhang Li of the Relief and Rescue Department of the Red Cross Society of China believes that the public’s awareness of first aid needs to be improved urgently. "In the past, everyone thought that pre-hospital first aid had to wait for 120. I was unprofessional and I could do nothing." Zhang Li pointed out that at the scene of an emergency, the scientific rescue of the first witness at the first time and the first scene is a very important part of pre-hospital first aid. Zhang Li revealed that this year, the Shanghai Red Cross made a questionnaire survey on AEDs to 10,000 college students in local universities. The result showed that about 60% knew about AEDs, only 38% knew about the configuration of AEDs in our school, and only 22% knew how to use them.

　　Shi Hong believes that different rescuers’ differences in operation timing control and operation details will bring controversy, and moral and legal issues cannot be avoided. Even the certification of operator qualification is controversial. At the same time, AED belongs to non-medical operation, but it plays a medical role and allows all people to operate. How to establish the identification system for medical and non-medical treatment is also a practical problem. Shi Hong said that excessive disputes over operational details will affect the work efficiency of the promotion.

　　"We not only lack first-aid knowledge and skills, but also first-aid equipment, such as first-aid kits and AEDs, and what we lack is first-aid awareness." Jia Dacheng, who has been engaged in medical emergency work for more than 30 years, said.

　　■ Standards are coming.

　　Public awareness of first aid has improved significantly.

　　Healthy China Action Promotes AED Popularization

　　Jia Dacheng has given lectures and training on first aid knowledge for thousands of institutions in various industries in China for many years. He is a senior expert in first aid popularization education in China. In the 1990s, after he first came into contact with the AED given by the US to Beijing Emergency Center, Jia Dacheng’s career was permeated with the popularization of AED to the public. Up to now, 70-year-old Jia Dacheng still carries AED with him when he goes out, one for emergency at any time, and the other for spreading first aid knowledge and concepts.

　　Compared with the 1990 s, he believes that the public’s awareness of first aid has improved significantly. "No one paid attention to it in the 1990 s, and no one came to the on-site training; Now I am actively looking for me to train. "

　　At present, the deployment of AEDs in public places has not been clearly defined. However, the good news is that relevant documents have been issued at the national level to promote the popularization of AEDs. The Healthy China Action (2019-2030) issued by the State Council this year mentioned that residents should be guided to learn and master the knowledge and skills of self-help and mutual rescue such as cardiopulmonary resuscitation. By 2022 and 2030, the number of people who have obtained the first aid training certificate will reach 1% and 3% respectively, and the primary and secondary school teaching staff will be trained as first aiders according to the ratio of teachers and students of 1:50. Improve the equipment standard of AED in public places, and configure an ambulance for every 50,000 people to shorten the first aid response time.

　　In October this year, when faced with a message from netizens about "accelerating the deployment of AEDs in public places", National Health Commission also responded — — "China has made some progress in promoting the public to use AEDs, but there is still a big gap compared with advanced countries. In the next step, the National Health and Wellness Commission will actively promote the implementation of the Healthy China Action, further strengthen cooperation with the Chinese Red Cross Society and other departments, coordinate relevant departments, jointly increase the investment in AED configuration, carry out universal training on AED and cardiopulmonary resuscitation, and scientifically guide the deployment and use of AED, actively promote the popularization of AED, and create a social atmosphere in which the public participates in first aid. "

　　"It’s much better than in previous years." Jia Dacheng said. "Everyone learns first aid, and first aid is for everyone." Encourage everyone to learn first aid knowledge and skills, which is also the concept that Zhang Li and others have always advocated.

　　Chengdu Business Daily-Red Star Journalist Wang Tian Yan Yu Cheng Zhao Qian

　　■ Visiting Chengdu

　　Some aeds cannot be turned on.

　　Official: It will be repaired and replaced in the near future

　　A few days ago, Chengdu Health and Health Commission announced the configuration point of AED in Chengdu. Some citizens found in Kuanzhai Lane that the unlocking place of AED equipment next to the Taitai specialty in Kuanxiang Ring was damaged and could not be opened normally. According to the description of the citizens, on December 3rd, a reporter from Chengdu Business Daily-Red Star came to Kuanzhai Lane, People’s Park and Mengzhuiwan Swimming Pool to learn about the management of local AED equipment.

　　On the afternoon of the 3rd, according to the AED configuration points announced by Chengdu Health and Health Commission, the reporter found the configured AED equipment at the entrance of No.27, Narrow Alley, next to the Huantai specialty in Kuanxiang, Kuanzhai Lane Scenic Area, but no equipment was found next to the old summer hot pot in Narrow Alley.

　　The unlocking place of the AED equipment configured next to the Taite in the wide alley ring has been damaged and cannot be opened. The reporter asked the surrounding businesses to understand that the equipment was not managed by the staff of the surrounding stores, and no staff was found around the equipment for management.

　　Equipment was found in the AED configuration points of People’s Park announced by Chengdu Health and Health Commission. However, when the reporter scanned the QR code according to the operation process on the device, he directly jumped to the WeChat WeChat official account of the device through WeChat. According to the prompt, the reporter scanned the code again. Although the prompt was successful in opening the device, it was not actually opened, and the prompt "Please use a safety hammer when the QR code cannot open the door" was printed on one side of the device.

　　At the Mengzhuwan Swimming Pool, the reporter found that all the equipment configured on the spot can be turned on. On each AED device, the prompt "Please contact the nearby staff to take the AED, and if the situation is urgent, you can break the glass to take it" was written, and the operating instructions of the AED automatic external defibrillator were placed under the equipment.

　　In response to the above situation, the reporter contacted the Chengdu Emergency Command Center. Chen Jing, deputy director of the Chengdu Emergency Command Center Office, said that according to the feedback from the public, he immediately contacted the management of Kuanzhai Lane to inspect the equipment, and found that the AED equipment next to the Kuanxiangzi Huantai specialty was indeed damaged and could not be opened normally. "In the near future, we will replace the AED equipment lock box in Kuanzhai Lane." Chen Jing told reporters that since the AED equipment deployed in Kuanzhai Lane is the first batch of equipment, it has been nearly three years since it was deployed, and it will be repaired and replaced in the near future.

　　Chen Jing also told reporters that "there are no relevant laws and regulations to guide the development of this work." Because Chengdu Emergency Command Center has no administrative power over public area managers, some public area managers do not cooperate with AED equipment management. "There may be some public areas that are not active in equipment management, but we will continue to strengthen communication with public area managers in the future to ensure that managers can better participate in equipment management. At the same time, increase training efforts, so that more professionals can assist the public to use AED equipment. "

Old photos： Chen Chong and Pan Hong, Shanghai actors from the 1980s.

What happened to the original DJ Yaqing’s old movies?

Spring has come, and the days of spring flowers are not far away. At this moment, I can’t help but think of the movie Hundred Flowers Garden in the 1980s, which is really colorful and beautiful. Today, let’s go back to the 1980s and feel the unique splendor and warmth of the movie stars at that time.

Twenty-two movie stars and 22 beautiful and rare old photos appeared in front of us in turn with the simple atmosphere of the 1980s. When you see familiar faces, I wonder if you will be moved for a long time in your hearts. Among these stars, who was your favorite male god or goddess?

Chen Chong, when I saw this old photo of her, the first word that came to my mind was innocence. Yes, Chen Chong came into our sight with this unique innocence. Looking back now, she didn’t see how mature and exquisite her acting skills were in the movie Little Flower, but because of her freshness, she touched the hearts of thousands of fans.

Cheng Xiaoying, unforgettable her charming smile, unforgettable her elegant temperament. Whether it is Morishita Photon in Sakura or Qumu Azhi in Dancing Love, they are all so graceful and charming.

Guo Kaimin, in the film studio in the 1980s, his resources were really good. Not only are the plays about one after another, but the partners are all beautiful women and big stars, such as yu zhang, Gong Xue, Liu Jia and Chen Yanhua. And his handsome, also left in the hearts of too many viewers.

Han Yueqiao, who doesn’t make many films, is not the most famous actress. But no one can deny that she is really beautiful, like a flower in spring.

Huang Meiying is a real beauty actress, but her star path is not smooth. Many films she starred in failed to meet the audience and missed many opportunities to become popular. It was not until the TV series "Desire" started that her fame increased greatly. In this year’s film Lost in Russia, she played the role of mother at the age of 70, and her wonderful performance was truly amazing. At the same time, I have to admit that she is the kind of actress who has been beautiful until she is old.

Bao Xun, a long-lost handsome actor, has played many characters on the screen in 1980s, such as Huang Yongliang in The Flowers Are Pretty, Lu Xiaofan in The Tenth Bullet Hole and Lin Yao in The Bitter Fruit.

Li Xiuming, an unforgettable name for the audience in 1980s, is the eternal goddess in many people’s hearts. This is her look in the movie Princess Peacock.

Liang Danni, the daughter of writer Liang Xin (the screenwriter of the film Red women soldiers) and the wife of Feng Yuanzheng. How young and beautiful she was then. Now she is 66 years old.

Lin Fangbing, another beautiful actress. The temperament is fresh and refined, and full of aura.

Pan Hong, the most unforgettable thing is her big eyes, quiet and beautiful, like stars in the night sky. I always thought that her natural actor, no matter what role she created, was so deeply rooted in people’s hearts. Lu Wenting in "Man to Middle Age" is still a classic that is hard to surpass.

Shao Huifang, a dancer, is refined in appearance and tall. He has starred in movies such as Ghost, The Mystery of R4, Trading under the noose, etc.

Jianlan Shi, a Legend of Tianyunshan, made her enter the hearts of thousands of audiences. The kind Feng Qinglan makes her the embodiment of beauty.

Tang Guoqiang, known as "the originator of small fresh meat", is not without reason. His handsome facial features are impeccable. This is his style in the movie Princess Peacock.

Tu Ruying didn’t make many films in the 1980s, but he left a deep impression on the audience.

Wan Qiong, another beauty star, appeared on the screen because of her leading role in the movie "The Official’s Ascension", and then she played roles in films such as Mute Gu, Happiness by Your Side, and The Fate of a Woman.

Wang Fuli, a well-known and favorite movie star in the 1980s, has a gentle smile deeply imprinted on the hearts of the vast number of fans.

Wang Qinbao, another beauty star in 1980s, once played Xiaolan in Junior, Bai Mei and Hongmei in Plum Blossom Towel, and Camellia in Magpie Ridge Tea Song.

Xiao Xiong always feels that many actresses don’t have the skill and smartness in her body, and her performances in the movies "They are in love", "Bitter Fruit", "Backlight", "On the Elevator" and "The Last Noble" are also remarkable.

Xie Fang, a big star who became popular in the 1950s, needs no introduction. In the 1980s, he also appeared in many films, such as The Second Handshake, Li Qingzhao, Clear Water Bay, Danshui Bay and so on.

Zhang Xiaolei, who once missed the Legend of Tianyunshan directed by Xie Jin, went to the screen and became popular because he played Ulan in the movie Yan Return.

Yu zhang, an actor full of aura, is the first golden rooster award double-winner. Its popularity in the 1980s was no less than that of any popular Hua Dan today. Until now, she is still the goddess in many people’s hearts.

Zhou Lina has big eyes, a pretty face and a flowery smile. In the 80′ s, the film Hundred Flowers Garden also had a different kind of beauty. This is her look in the movie "The Spy".

Familiar faces, moving pictures, let us go back to the spring of the 1980s, and once again feel the memories and feelings that were brought to us in the past light and shadow world. Among the 22 stars on display today, who is the most unforgettable goddess? Welcome everyone to interact with more fans and netizens through the message area. I’m Yaqing. Thank you again for your attention and reward. Let’s meet at the same time tomorrow. Goodbye.

This article was originally written by DJ Yaqing. Please don’t copy it without permission! Offenders will be prosecuted! What is more tragic than plagiarism is that even copying can’t copy the essence! !

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Netease Cloud Music is valued at 8 billion, but it is not Netease.

Every edited reporter Zhao Na every edited Lu Xiangyong.　　　　

Graywatermark.thumb_head

Every reporter Zhao Na, every editor Lu Xiangyong.

Recently, Netease Cloud Music announced that it had received 750 million yuan of Series A financing. After this round of financing, Netease Cloud Music was valued at 8 billion yuan. As a leading Internet technology and online game service provider in China, in 2016, Netease’s net income was 38.179 billion yuan, of which the net income from online games was 27.98 billion yuan, accounting for 73.29%. However, Netease has been building non-game products, and Netease Koala Haibao and Netease YEATION have been well evaluated in the market. There is reason to believe that Netease Cloud Music is another non-game signboard created by Netease.

National business daily reporter found that Netease Cloud Music is not operated by Netease, but by another company whose CEO Ding Lei holds 99%.

The main operator is Hangzhou Ledu.

When you open Netease Cloud Music on the computer, you can find that it uses Netease’s second-level domain name (music.163.com), and it shows "Copyright by Netease Company" at the bottom of the homepage, but the operation is undertaken by a company called Hangzhou Ledu Technology Co., Ltd. (hereinafter referred to as Hangzhou Ledu). Netease Cloud Music’s corresponding Network Culture Business License is Zhewangwen [2015] No.0415135, which also belongs to Hangzhou Ledu. Its business scope is "using information network to operate music and entertainment products" and its type is "mainland operating Internet cultural units".

According to the industrial and commercial data, the shareholders of Hangzhou Ledu are Ding Lei and Zhu Yiwen, natural persons, and their contributions are 9.9 million yuan and 100,000 yuan respectively, accounting for 99% and 1%. The legal representative of Hangzhou Ledu is Zhu Yiwen, registered on December 25, 2014, with a registered capital of 10 million yuan. Zhu Yiwen is also the executive director and general manager of the company.

According to public reports, Zhu Yiwen is currently the CEO of Netease Cloud Music.

So, where is the ownership right of Netease cloud music products at present? The reporter found that on the Apple App Store, the copyright of Netease Cloud Music belongs to Netease (Hangzhou) Network Co., Ltd., and the developer is Hangzhou Netease Cloud Music Technology Co., Ltd. (hereinafter referred to as Hangzhou Netease Cloud Music). The legal representative of Hangzhou Netease Cloud Music is also Zhu Yiwen, with a registered capital of US$ 3.75 million, and the shareholder is Cloud Village Limited, with a capital contribution ratio of 100%.

It is worth noting that the information further inquired by the reporter through the Companies Registry of the Government of the Hong Kong Special Administrative Region shows that the company category of Yuncun Co., Ltd. is a private company limited by shares, and its establishment date is February 22, 2016. The share capital, both issued and paid, is HK$ 1. The list of directors only lists Ding Lei as a natural person.

Zhao Zhanling, a well-known IT and intellectual property lawyer, said in an interview with national business daily that Hangzhou Ledu is the main operator of Netease Cloud Music and the main holder of the Network Culture Business License. However, Hangzhou Ledu has only two natural person shareholders, including Ding Lei, and Ding Lei is the absolute controlling shareholder, which shows that there is no equity relationship between Netease and Hangzhou Ledu, but only authorizes Netease Cloud Music to use the trademark, domain name and other intellectual property rights of Netease.

How to determine the future ownership

The company introduction page of Netease Cloud Music shows, "Hangzhou Netease Cloud Music is an Internet technology company under Netease. Netease Cloud Music is a music product developed by it. " From a legal point of view, if the owner and the operating entity are separated, is it compliant?

Zhao Zhanling told reporters that this practice is "not illegal and legal", and there should be an intellectual property license agreement between them. Netease allows Hangzhou Ledu to use its trademark and other intellectual property rights, and Hangzhou Ledu may pay a certain usage fee, and there may also be other business cooperation agreements between them.

National business daily reporter found in Netease’s 2016 annual report (FORM 20-F) recently submitted to the US Securities and Exchange Commission (SEC) that Netease cloud music was summarized as "our online music social network" and classified into email, e-commerce and other businesses. In addition, the operating cost part of the above annual report shows that the information cost of Netease in 2016 increased by 4.4 million US dollars to 38.4 million US dollars compared with 2015, mainly due to the amortization of license fees related to cloud music.

Another detail shows that the registration time of Hangzhou Netease Cloud Music was May 18, 2016, and the establishment date of Yuncun Co., Ltd. was earlier on February 22, 2016. In this regard, Zhao Zhanling’s judgment does not rule out the possibility that the latter is specially set up for Hangzhou Netease Cloud Music.

On April 11th, Netease Cloud Music announced a round of financing of 750 million yuan. Ding Lei said that the A round of financing is the first step for Netease Cloud Music to make a bigger dream. With the participation of strategic partners, it will definitely create a more remarkable music career.

In this context, if Netease Cloud Music grows bigger after financing, how to determine the ownership? In this regard, Zhao Zhanling said that Netease Cloud Music belongs to its shareholders. After financing, the control right of Netease Cloud Music is determined by the equity institution after financing and the relevant agreement of the financing agreement.

On the morning of April 23rd, the reporter of national business daily contacted Netease to understand the situation on issues related to the equity of Netease Cloud Music, as well as the share proportion of Netease after financing Netease Cloud Music, industry consolidation and profit planning. As of the reporter’s deadline, Netease did not respond positively. It said that "the investment in mergers and acquisitions should be confirmed by relevant people, and it may be that the time difference problem has not been contacted".

Maintaining a healthy life and behavior style of cancer survivors significantly reduces the risk of death.

Original GlobalMD global doctors organization

The latest research confirms that following the American Cancer Society’s guidelines on healthy nutrition and activities for cancer survivors, controlling weight/obesity, moderate exercise, healthy diet and limiting alcohol consumption can significantly reduce all-cause and cardiovascular diseases and cancer mortality. Pay attention to details.

Reading abstracts

The American Cancer Society (ACS) recently issued a guide to healthy nutrition and activities for cancer survivors, suggesting that survivors should control their weight, exercise moderately, eat healthily and limit alcohol consumption. Numerous studies have shown that the risk of death of obese non-smokers and related cancer patients who follow the guidelines is significantly reduced.

The researchers followed nearly 4,000 cancer survivors diagnosed from 1992 to 2002 (with an average age of 67.6 years). After a median follow-up of 15.6 years, they adopted a composite scoring system of 0-8, covering the compliance evaluation of BMI, exercise, diet quality and alcohol intake.

The study found that the score of 6-8 group decreased by 24% compared with that of 0-3 group, among which the cardiovascular mortality decreased by 33% and the cancer-related mortality decreased by 21%. It is worth noting that BMI control (keep 18.5-24.9 kg/m2; ) Maintaining moderate-intensity exercise of ≥150 minutes per week is the most significant contribution to the improvement of survival rate.

Longitudinal analysis shows that those who keep high compliance (score ≥5) or actively improve their lifestyle after diagnosis are 18%-22% lower than those with long-term low compliance (score < 5) in all-cause mortality.

This study quantifies for the first time the tertiary preventive value of lifestyle intervention on non-smoking obese people and related cancer groups, especially the health behavior adjustment after diagnosis can produce 18% survival benefits.

The data of this study reveals that even if health management is implemented after diagnosis, the mortality rate of cardiovascular diseases can still be reduced by 27%. The results of this study also provide a first-class evidence-based scientific basis for the formulation of the clinical path of tumor rehabilitation.

Original title: "Cancer survivors maintain a healthy life and behavior significantly reduce the risk of death"

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It’s about going home for a trip during the Spring Festival, starting school on holiday and returning to work after the holiday … Spring Festival travel rush’s work plan is coming!

　　On the 27th, the State Council issued the Overall Work Plan for the Prevention and Control of Epidemic Situation in Spring Festival travel rush and the Guarantee of Transport Services in 2023. In 2023, the comprehensive transportation of Spring Festival travel rush will start on January 7th and end on February 15th, with a total of 40 days. The main points of the Plan are as follows &darr;

　　In 2023, Spring Festival travel rush will face new situations and changes.

　　First, the passenger flow in Spring Festival travel rush will rebound from the low level, and the total passenger flow may increase substantially;

　　Second, the transportation of key materials such as energy and grain and materials such as medical care and people’s livelihood is arduous;

　　Third, during the period of Spring Festival travel rush, personnel flow and freight logistics activities were intensive, and personnel cross-activities were frequent.The risk of infection of transportation employees is high;

　　Fourth, the long-term low-load operation of transportation has increased the security risks of facilities, equipment and personnel.If management is not in place, accidents in transportation safety production may be prone to occur frequently.

　　"Program" requires: to solidly promote the prevention and control of epidemic situation and transportation service guarantee of comprehensive transportation in Spring Festival travel rush,Do everything possible to ensure the efficient and smooth transportation of key materials such as energy and grain, and materials such as medical care and people’s livelihood, and do everything possible to get through the whole chain and all links of passenger travel from the starting point to the end point to ensure the safe departure and smooth return of passengers.

　　Take multiple measures to ensure the orderly travel of staggered peaks

　　All localities should implement it scientifically and accurately.Optimization measures for epidemic prevention and control and "Class B and B management" measures.

　　No more negative certificates and health codes for nucleic acid testing, no more landing inspection and no more temperature measurement for passengers.

　　Passenger service shall not be suspended or restricted at will, and normal traffic of vehicles and ships shall not be restricted at will.

　　It is strictly forbidden to illegally set up all kinds of check card points on the highway and intercept vehicles at will., to speed up the resumption of suspended passenger services.

　　All localities can take appropriate temporary measures to restrict the flow of people in accordance with the law, and guide the public to avoid traveling at the peak of the epidemic as much as possible.

　　The implementation of motor vehicle tail number limit policy of the city, according to the needs.To study the measures to suspend the implementation of motor vehicle tail number restriction in stages during the introduction of Spring Festival travel rush.

　　Ensure that visiting relatives go home for the New Year and return to work in an orderly manner.. All localities can explore the implementation of flexible vacation and off-peak vacation policies.Reduce the pressure on the public to concentrate on travel.

　　The centralized export and import places of migrant workers should strengthen the connection and cooperation.Guide and ensure the safe and healthy travel of migrant workers returning to their hometowns.

　　If the demand for returning home and returning to work is relatively concentrated and qualified, it can be combined with the actual organization."Point-to-point" transportation of migrant workers, such as chartered cars, special trains (including carriages) and charter flights.

　　Further optimize the prevention and control of epidemic situation on campus and the arrangement of teaching plan, and arrange for returning to school in spring to avoid peaks and peaks. In principle,Colleges and universities should avoid starting school during Spring Festival travel rush as much as possible.. If it is really necessary to start school during the period of Spring Festival travel rush, we should adhere to the principle of "one place, one case", "one school, one policy" and "one level, one policy" to organize the start of school and return to school, and try to avoid the peak period of return passenger flow in Spring Festival travel rush.

　　Where the demand for leaving school and returning to school is relatively concentrated and qualified,We can organize "point-to-point" transportation such as student chartered cars, special trains (including carriages) and charter flights.

　　All localities should further strengthen the analysis of big data, carefully study the self-driving travel situation of the masses during Spring Festival travel rush, and guide the self-driving personnel to reasonably choose the travel route, time and destination to avoid peak travel.

　　All localities should release cultural tourism consumption policies during the Spring Festival in advance,Strictly implement the optimized epidemic prevention and control measures in the cultural tourism industry.

　　Strengthen data monitoring, share information such as the size and capacity of tourists in a timely manner,Coordinate the connection between transportation and tourism and the allocation of transportation capacity.

　　In view of large-scale epidemic infection, bad weather, safety accidents, emergencies, etc.Formulate and improve the emergency plan for the disposal of stranded tourists, and do a good job in the timely and orderly evacuation of stranded tourists..

　　In view of the centralized travel needs such as visiting relatives and friends and going to the market in rural areas, by encrypting the service frequency of urban and rural public transport and rural passenger transport lines, extending the operation time, running the market class, and increasing the appointment response service,Increase the rural transportation service guarantee.

　　Improve the operational efficiency of transportation logistics

　　Strictly implement the optimization policy of ensuring smooth traffic and logistics.Incorporate transportation logistics practitioners into the "white list" management.

　　No longer check the negative nucleic acid test certificates and health codes of truck drivers and crew members,No longer carry out landing inspection for cross-regional mobile truck drivers.

　　It is strictly forbidden to shut down the transportation and logistics infrastructure without authorization, and it is strictly forbidden to restrict transportation services in any form.

　　Key ports, airports, railway cargo terminals, logistics parks, postal express distribution centers, and operational management units such as navigation channels, navigation structure, and pilot agencies should improve their emergency plans.Establish a front-line personnel reserve team, and if necessary, implement a rotation system to conduct closed management.To ensure the stable operation of key logistics hubs in emergencies.

　　All localities should strengthen the dispatch of transport capacity and make emergency preparations.Make every effort to ensure the efficient operation of trunk transportation, collection and distribution of key materials such as energy, grain, agricultural machinery and agricultural materials this winter and next spring..

　　Strengthen the joint guarantee of highway services for transportation of key materials,Resolutely prevent long-term and large-scale vehicle congestion.

　　Strictly implement the "green channel" policy for the transportation of fresh agricultural products, and ensure the free and convenient passage of vehicles legally loaded with fresh agricultural products in the national unified catalogue and Covid-19 vaccine cargo transportation vehicles..

　　Where it is really necessary to close some areas of expressways and water service areas,It is necessary to ensure the normal operation of basic public service functions such as refueling and toilet use.

　　It is strictly forbidden to suspend or refuse to change the crew of ships sailing internationally at will.To ensure the smooth supply chain of international maritime logistics and the legitimate rights and interests of crew members.

　　Scientifically and accurately prevent and control the epidemic situation in Spring Festival travel rush

　　To formulate and implement guidelines for the prevention and control of novel coronavirus infection in Spring Festival travel rush.Fully implement the optimization measures for epidemic prevention and control and the measures of "Class B and B management".

　　Conditional highway service areas can be set up with parking areas for vehicles and rest areas for drivers and passengers.Provide drinking water, toilet and rest services for people with fever and other symptoms.

　　Organize front-line employees in transportation to carry out health monitoring and implement symptom management.. Employees should minimize social contact, such as fever and other symptoms, and carry out antigen or nucleic acid testing when necessary.

　　In principle, personnel with fever and other symptoms are not arranged to engage in transportation activities.; For those who have had symptoms for more than 7 days or have disappeared, they can resume their work under strict personal protection. The principle of strict prudence should be adhered to when drivers take up their posts.

　　All localities should carry out extensive publicity,Guide the public to travel rationally and at the wrong peak during their stay in Spring Festival travel rush.

　　Passengers are traveling.Wear a mask all the time, actively reduce gathering, adhere to good hygiene habits such as washing hands frequently, coughing etiquette and keeping interpersonal distance.

　　The emergence of transportation business service unitsnewWhen infected with coronavirus, the workplace is not sealed and controlled, and it is not isolated from the staff in the workplace.When there is a sudden large-scale epidemic, the key post reserve team will be activated in time., timely dispatch and put into use reserve forces,Ensure that the key hub stations will not be shut down, the service of important transportation corridors and lines will not be interrupted, and the transportation of key materials will not be interrupted during Spring Festival travel rush.

　　On safety supervision and emergency response in Spring Festival travel rush.

　　Fully consider the particularity and complexity of comprehensive transportation in Spring Festival travel rush in 2023,We attach great importance to the potential safety hazards caused by long-term shutdown or low-frequency operation of transportation tools and unfamiliar driver skills, and attach great importance to the risk challenges brought by bad weather and large-scale passenger flow during Spring Festival travel rush.Take targeted measures in all directions and in the whole chain to prevent and contain all kinds of accidents to the maximum extent.

　　Guide and urge transportation enterprises to comprehensively inspect and maintain all the transportation tools, facilities and equipment put into Spring Festival travel rush,Resolutely put an end to the "sick" operation of means of transport and facilities.

　　Hidden dangers of major problems such as illegal operation, "three overloads and one fatigue", according to the law and regulations, resolutely curb the occurrence of serious accidents, and resolutely avoid the continuous occurrence of serious accidents.

　　All localities should guide and urge transport enterprises,Establish and strictly implement the daily health status reporting system for employees.When necessary, "two points and one line" management can be implemented for front-line employees such as drivers to minimize the infection rate.

　　▌ This article Source: CCTV News WeChat WeChat official account (ID: CCTV News Center)

　　Producer/Editor-in-Chief Chai Jing/Zhan Xing Cen

　　Desk reporter/Tang Ying editor/Xu Xiaowei cctv news

In 2019, the driver’s license was automatically downgraded？ Hebei Traffic Management Bureau responded： false news!

　　In 2019, the driver’s license was automatically downgraded? Provincial Traffic Management Bureau responded: false news!

　　Hebei News Network (Reporter Gao Shan) Recently, the news about "implementing the new driver’s license regulations in 2019" has been widely circulated in WeChat friends circle and some self-media platforms. Among them, the most concerned is the news that "since 2019, the driver’s license has been automatically downgraded".

　　According to the news circulating on the Internet, the vehicle management office will downgrade the owner’s highest driver’s license if the driver who holds the driver’s license from 2019 has the following violations: the first one is the A-class and B-class driver’s license holder, who has a major accident with the main responsibility; The second is that the holders of Class A and Class B driver’s licenses have been deducted 12 points within one cycle; The third is that the holders of Class A and Class B driver’s licenses have not participated in the annual inspection for three consecutive scoring cycles; The fourth is that after the driver reaches the age of 60, the vehicle management office will automatically reduce the driver’s license to C1 driver’s license. In addition, it is reported that if the driver’s driver’s license is reduced to C1 driver’s license and the above behavior still occurs, C1 driver’s license will be cancelled and become waste paper.

　　So, are all these news true? In response, the Provincial Traffic Management Bureau responded that there are indeed provisions for the cancellation and downgrade of driver’s licenses, but they are not new regulations, and the specific provisions are also different from rumors.

　　According to reports, according to the existing laws and regulations, drivers who hold driver’s licenses for large buses, tractors, city buses, medium-sized buses and large trucks should cancel their driving qualifications for the highest permitted driving type in one of the following three situations: if a traffic accident causes death and bears the same responsibilities, it does not constitute a crime; Having scored 12 points in a scoring cycle; Failing to participate in the examination for three consecutive scoring cycles.

　　"This regulation has been implemented since January 1, 2013 and has been implemented for six years. It is not a new regulation." Yu Shiqiang, the Propaganda Section of the Provincial Traffic Management Bureau, said that as for the rules of demotion, it is not the case of online transmission.

　　"In fact, the holders of Class A and Class B driver’s licenses are killed in a traffic accident and bear the same responsibilities. If they do not constitute a crime, they will meet the conditions for cancellation and demotion. When the holders of Class A and Class B driver’s licenses fail to score points within a scoring cycle, the scoring cycle may be exempted from verification. Therefore, it is not rigorous to say that three consecutive scoring cycles will be downgraded without verification. In addition, the C1 driver’s license will not become waste paper after being recorded for 12 points, but must take the perfect score study and the subject one exam. " Yu Shiqiang explained.

　　Yu Shiqiang told reporters that drivers over 60 years old are allowed to drive, for example, drivers over 60 years old are not allowed to drive large buses, tractors, city buses, medium-sized buses, large trucks, trolleybuses and trams, and those over 70 years old are not allowed to drive low-speed trucks, tricycles, ordinary tricycles, ordinary two-wheeled motorcycles and wheeled self-propelled vehicles. When the driver reaches the corresponding age, he should go to the vehicle management office to get the corresponding quasi-driving driver’s license, which will not be automatically downgraded.

　　The Provincial Traffic Management Bureau reminds the majority of drivers that rumors about traffic regulations will appear every once in a while. Please ask netizens to take the official information as the standard, and don’t pass it on.

How to choose which one is more worth starting with, Corolla Twin Engine or Ralink Twin Engine？

In the car market, the dual-engine and the car have attracted much attention. Below, I will compare the characteristics of these two models in detail from the perspectives of power performance, fuel economy, interior quality and high-tech configuration, so as to help you make a wise choice.

First, the dynamic performance:

Double engine: equipped with advanced hybrid power system, the power output is smooth and efficient. The combination of electric drive and gasoline engine makes the acceleration more rapid, and it also has a certain pure electric driving mode, which is suitable for urban driving and short-distance travel.

Toyota Ralink Twin Engine: Ralink Twin Engine also adopts Toyota’s hybrid power system, which has excellent power performance. Its power output is relatively smooth, and it also has a pure electric driving mode, which can realize zero-emission driving in cities.

Second, the fuel economy:

Toyota Corolla Twin Engine: The Corolla Twin Engine performs well in fuel economy. The advantages of hybrid power system make it more economical in fuel consumption, especially suitable for consumers who often drive in cities and commute for a long time.

Toyota Ralink Twin Engines: Ralink Twin Engines also have certain advantages in fuel economy. The high efficiency of hybrid power system makes it perform well in fuel consumption, which is suitable for consumers who pursue economy.

Third, the interior quality:

Toyota Corolla Twin Engine: The interior of Corolla Twin Engine pays attention to practicality and comfort. High quality materials and exquisite decoration create a comfortable interior environment for drivers and passengers. The design of the center console is modern.

Toyota Ralink Double Engine: Ralink Double Engine is also famous for its practicality and quality sense of interior. High quality materials and comfortable seats provide a comfortable and practical interior environment for drivers and passengers. The center console design pays attention to practicality.

Fourth, high-tech configuration:

Toyota Corolla Twin Engine: Corolla Twin Engine has certain advantages in high-tech configuration. Equipped with rich intelligent driving assistance system, multimedia entertainment function and high-quality sound system, it provides more convenience and comfort for drivers.

Toyota Ralink Double Engine: Ralink Double Engine also performed well in high-tech configuration. It has introduced the latest intelligent driving technology, interconnection function and safety configuration, making it more competitive in technology.

In a word, both Toyota Corolla and Toyota Ralink have their own characteristics, and the choice depends on personal needs and preferences. If you pursue efficient power performance, excellent fuel economy, practical interior and rich high-tech configuration, Toyota Corolla twin engines may be more suitable for you. If you are more interested in smooth power output, excellent fuel economy, comfortable interior and high-level technology configuration, Toyota Ralink twin engines may be more suitable.

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